The best defined and most widely used stem cell treatment is hematopoietic (or blood) stem cell transplantation, for example bone marrow transplantation, to treat certain disorders of the blood and immune system or to rebuild the blood system after treatments for some types of cancer. For example, hematopoietic stem cells are a type of adult stem cell found in bone marrow. Make new red blood cells, white blood cells and other types of blood cells. Doctors have been performing stem cell transplants, also known as bone marrow transplants, for decades using hematopoietic stem cells to treat certain types of cancer.
At this time, the most commonly used stem cell-based therapy is bone marrow transplantation. Blood-forming stem cells in bone marrow were the first stem cells identified and were the first to be used in the clinic. This life-saving technique has helped thousands of people around the world who had had blood cancers, such as leukemia. In addition to their current use in cancer treatments, research suggests that bone marrow transplants will be useful in treating autoimmune diseases and helping people tolerate transplanted organs.
Other adult stem cell-based therapies are currently in clinical trials. Until those trials are completed, we will not know which type of stem cell is most effective in treating different diseases. The best example of an adult stem cell is the blood stem cell (hematopoietic stem cell). When we refer to a bone marrow transplant, a stem cell transplant or a blood transplant, the cell that is transplanted is the hematopoietic stem cell or blood stem cell.
This cell is a very rare cell found mainly in the bone marrow of an adult. Mesenchymal stem cells do this by influencing tissue repair through paracrine effects (cell signaling to change the behavior of existing cells) or direct cell-to-cell contact. Embryonic stem cells are obtained from early-stage embryos, a group of cells that forms when eggs are fertilized with sperm in an in vitro fertilization clinic. Therapeutic cloning, also called somatic cell nuclear transfer, is a technique to create versatile stem cells independent of fertilized eggs.
Scientists test cells by first developing an animal model that mimics human disease and then implanting the cells to see if they help treat the disease. Scientists may be able to alleviate these concerns by using a new method that can convert adult stem cells into pluripotent stem cells, which can be transformed into any cell type. Scientists are also working on ways to develop stem cells from other cells, using genetic “reprogramming” techniques. Stem cell therapy is generally considered a safe procedure with minimal complications; however, as with any medical procedure, complications can occur.
Unregulated clinics around the world offer stem cell therapies that may not live up to expectations and may worsen a patient's health. While stem cell therapy does not necessarily provide a cure for these conditions, the premise is to allow the body to heal well enough to mitigate the symptoms of the conditions for extended periods. This new technique may allow the use of reprogrammed cells instead of embryonic stem cells and prevent the immune system from rejecting the new stem cells. You may be wondering what stem cells are, how are they used to treat diseases and injuries, and why they are the subject of such intense debate.
Stem cells can be administered in various ways; IV stem cell therapy (intravenous administration), intrathecal (directly into the spinal canal), on-site injections into problem areas (knee, hips, hands, etc. Researchers have identified stem cells in samples of amniotic fluid taken from pregnant women for testing or treatment, a procedure called amniocentesis. For example, stem cells from a twenty-year-old person are not as high quality as new cells obtained from umbilical cord tissue. According to GMP standards, a cell line must be manufactured so that each group of cells grows in an identical, repeatable and sterile environment.
Studies have shown that stem cells can regenerate damaged or diseased tissues, reduce inflammation and modulate the immune system, promoting better health and quality of life. . .